National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
SARS (Severe Acute Respiratory Syndrome) Coronavirus-2 (SARS-CoV-2) is a highly contagious virus that infects humans and several mammals, resulting in Coronavirus disease-19 (COVID-19). Every time the virus replicates, there is a chance that a mutation will occur, resulting in the development of a phylogenetically distinct strain. The emergence of several strains of this virus has resulted in a second wave of the epidemic and a tremendous amount of strain on the national surveillance and health systems. However, if we want to mount the most effective resistance against COVID-19, we must do so against variants as well, and for doing so, we must first consider the virus's evolutionary capacity. To foresee the variants that will emerge, it is important to understand how SARS-CoV-2 mutates and what limits its evolution. So far, the receptor-binding spike protein has been the focus, but the virus is a trailblazer, expressing 26 proteins that communicate with a broad variety of host factors, so the possibilities for evolution are numerous and uncertain. A triple mutant strain could be India's next challenge, and collecting as much information as possible about it is crucial to defeat it before it creates havoc. To bring an end to the COVID-19 pandemic, widespread immunity to SARS-CoV-2 will be needed.
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