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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2021.10(3): 1339-1346
DOI: https://doi.org/10.20546/ijcmas.2021.1003.164


Seroprevalence of Hepatitis B and Hepatitis C Viral Infections in Thalassemia Patients Undergoing Multiple Blood Transfusions in a Tertiary Care Hospital
Anupriya Yadav*, Rameshwari Bithu, Manju Yadav and Rakesh K. Maheshwari
Department of Microbiology, Sawai Man Singh Medical College and Attached Hospitals, Jaipur, Rajasthan, India
*Corresponding author
Abstract:

Thalassemia is one of commonest hereditary disease worldwide, prevalent in humid climates and affects all races. The Transfusion Dependent Thalassemias require regular blood transfusion to survive. The thalassemia patients require lifelong blood transfusion on regular basis- usually administered every 2 to 5 weeks. Due to regular blood transfusion, transfusion transmitted disease e.g. Hepatitis B Virus (HBV), Hepatitis C virus (HCV) and Human Immunodeficiency Virus (HIV) infections can occur. Aim of the study is to evaluate the prevalence of Hepatitis B & C viral infections transmitted by blood transfusion among thalassemia patients. Observational study conducted over a period of one year, a total of 118 thalassemia patients were studied. Patients were screened for Hepatitis B and Hepatitis C viral infections by rapid test kits and the conformation was done by ELISA. Out of 118 thalassemia patients, 74 (62.7%) were male and 44 (37.3%) were females. Out of them 36 (30.5%) patients were anti–HCV reactive and none was reactive for HBsAg. Multi transfused patients must be regularly tested and monitored to ensure safe blood transfusion practices. The patients should be encouraged to stick to one thalassemia management centre. Stringent donor screening, use of modern advents such as NAAT (nucleic acid amplification test) and PCR for screening of blood bags for HBV and HCV infection and bringing awareness in community will help in reducing the problem statement.


Keywords: Hepatitis B and Hepatitis C Viral Infections, Seroprevalence
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How to cite this article:

Anupriya Yadav, Rameshwari Bithu, Manju Yadav and Rakesh K. Maheshwari. 2021. Seroprevalence of Hepatitis B and Hepatitis C Viral Infections in Thalassemia Patients Undergoing Multiple Blood Transfusions in a Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 10(3): 1339-1346. doi: https://doi.org/10.20546/ijcmas.2021.1003.164