National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Infection rates in ICU have been found to be high among hospital acquired infections. The most commonly used wide group of antimicrobials is beta-lactams. However, increasing trend of resistance to various beta lactams among uropathogen is mainly mediated by beta-lactamases which is of majorconcern . This study was done to determine the prevalence of Extended spectrum beta lactamase producing Gram negative bacilli among urine culture isolates and their trends of antibiotic susceptibility patterns which is prevalent among these isolates in our Institute from ICU patients. The study was conducted in the Department of Microbiology at Sree Balaji Medical College and Hospital from December 2017 to December 2018.Total number of urine samples received were 316 in our microbiology laboratory from ICU. Isolates were identified by Colony morphology, Gram stain and standard biochemical reactions. Antibiogram was determined by Clinical and Laboratory Standards Institute (CLSI) guidelines. Total positive culture present in the study 68 (21.51%). Among these culture positive isolates 22 were gram positive (32.35%) isolates and 46 were gram negative (67.64%).Among these 46 isolates of gram negative, 17 (36.95%) were ESBL producers. The most common isolate was E.coli, Klebsiella pneumoniae species. All the extended beta lactamase producing gram negativebacilli isolates showed 100% susceptibility to Carbapenems, Colistin and Polymyxin-B.
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