National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Fibrinolytic enzymes help in dissolving the fibrin clots and they have the potential use in the treatment of harmful cardiovascular diseases. High efficient fibrinolytic enzymes are produced from the fibrinolytic microbes under extreme environmental conditions. In the present work, microorganism strain that helps in the production of fibrinolytic enzymes were isolated and screened from the soil waste. Five isolates i.e., SWN-15, SWN -25, SWN -35, SWN -45 and SWN -55 were subjected to macroscopic characteristics The isolated organism was cultured in the sterile media at 37ºC for 24 hrs. The selected isolates were subjected to caseinolytic, gelatinolytic and fibrinolytic activities was done. The fibrinolytic activity of isolates SWN 25 and SWN 55 was higher than that of caseinolytic and gelatinolytic activities. The selected isolates were tested with modified media composition and at different pH values. Isolate SWN-55 showed good enzyme productivity (13.1 + 2.6) U/ml at pH 8.0. Also the biochemical study indicated the isolate SWN 55 is similar to that of Streptomyces sp. with fibrinolytic function.
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