National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
In present study, we had isolated the bacteriophages from sewage material of various livestock farms, NDVSU, Jabalpur Madhya Pradesh. The recovered bacteriophages subjected for the identification with electron microscopy. The isolated bacteriophages had shown icosahedral symmetry. Phage had hexagonal head with the size of 52.20 nm in diameter and long tail of 109 nm. They were classiï¬Âed as a member of the Myoviridae family under the order of Caudovirale. These recovered bacteriophages were subjected to spottest to know the antibacterial activity against bacterial pathogens. All the recovered phage lysate showed the antibacterial activity specifically against the Staphylococcus aureus isolated from chronic septic wounds. These isolates of bacteriophage had limited host range due to their nature to infect the specific host. There was few isolates (ØVS4 ØVS5 and ØVS9) of bacteriophages were showing the lytic activity against the other microbial organism like Bacillus spp and E. coli. ØVS4, ØVS5 and ØVS9 three isolates of bacteriophage had broad host range. In vitro antibacterial activity of phage lysates can be used as a potential therapy against multiple drug resistant pathogens in the current era of antibiotic resistance crisis.
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