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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(9): 3496-3508
DOI: https://doi.org/10.20546/ijcmas.2020.909.434


Anti-cancer and Anti-microbial Potential of Nutraceutical Rich Under utilized Herb Portulaca Oleracea from Kashmir Region
Imtiyaz Murtaza1*, Navreen Rashid1, Omi Laila1, Nisar Ahmad Ganie2
and M. Younus Wani2
1Biochemistry and Molecular Biotechnology Laboratory,
Division of Basic Sciences and Humanities, SKUAST-K, J&K, India
2CoTS, Mirgund, SKUAST-K, J&K, India
*Corresponding author
Abstract:

Portulaca oleracea (commonly known as Nunner in Kashmir) is an underutilized wild vegetable in the Kashmir region. This vegetable is believed to be highly nutritional and quite health beneficial, however, has remained highly unexplored. Therefore, in the current study, the nutraceutical composition as well as antimicrobial and anticancerous potential of wild edible herb Portulaca oleracea (common purslane) was determined in its fresh as well as dried form. The results revealed that dried form comparatively contains higher carbohydrates (25.1±0.173%), crude protein (19.83±0.145%), crude fat (4.02±0.011%), crude fiber (7.19±0.017%), total soluble sugars (3.56±0.012%), reducing sugars (3.16±0.012%) and non-reducing sugars (0.40±0.023%). In addition, Portulacaoleracea proved to be a rich source of calcium (1366.66±0.120mg/100g), magnesium (943.93±0.713mg/100g), sodium (153.63±0.145mg /100g) and iron (47.66±0.088mg/100g) content. The nutraceuticals were also found to be present in appreciable amounts includingtotal phenols 385.96±0.744mg/100g, total flavonoids 98.66±0.120mg/100g and total anthocyanins 881.76±0.088mg/100g, respectively. The antimicrobial assay demonstrated that P. oleracea has great potential to be used as an antimicrobial agent against Staphylococcus aureus and E. coli (EPEC) pathogens. Interestingly, the aqueous extracts of dried P. oleracea exhibited potent dose and time dependent cytotoxic effects against HL-60, MOLT-4 and T47-d cancer cell lines under in vitro conditions. Thus, through this study, we provide a scientific basis for nutraceutical rich Portulaca oleracea from Kashmir valley for its folklore or ethno-medicinal uses, and for its further exploitation as a highly useful alternative strategy for antimicrobial and anti-cancer drug development or as an adjuvant to existing therapies.


Keywords: Portulaca oleracea, Nutraceuticals, Antimicrobial, Anticancerous, Medicine
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How to cite this article:

Imtiyaz Murtaza, Navreen Rashid, Omi Laila, Nisar Ahmad Ganie and Younus Wani. M. 2020. Anti-cancer and Anti-microbial Potential of Nutraceutical Rich Under utilized Herb Portulaca oleracea from Kashmir Region.Int.J.Curr.Microbiol.App.Sci. 9(9): 3496-3508. doi: https://doi.org/10.20546/ijcmas.2020.909.434