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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(9): 3225-3231
DOI: https://doi.org/10.20546/ijcmas.2020.909.399


In-vitro Antibacterial Activity of the Product ‘Xembran®’ against Helicobacter pylori
Pankaj P. Gaonkar1*, A. M. Das2, Maithili Rembhotkar3 and Amit Purnendu Goel3
1Department of Veterinary Pathology, Nagpur Veterinary College, Nagpur, Maharashtra India
2Gayatri Laboratory, Mumbai, Maharashtra India
3Grocare, Pune, Maharashtra, India
*Corresponding author
Abstract:

Helicobacter pylori is a global pathogen, ultimately affecting fifty percent of the population of the world. It has developed resistance to routinely used antibiotics. Subsequently, it is imperative to locate an alternative treatment for Helicobacter pylori.  Xembran®, a combination of Myristica fragrans and pure Shankha Bhasma was tested for its anti-Helicobacter pylori activity.  The activity of Xembran was determined by disc diffusion and the minimum bactericidal concentration method. The complete inhibition of Helicobacter pylori was achieved at a concentration of 70mcg by the disc diffusion method. Xembran was able to show greater activity against Helicobacter pylori with an increase in contact time. However, 0.5% concentration was adequate to execute the bactericidal effect on Helicobacter pylori with a contact time of 20 minutes.  Xembran can serve as an alternative to routinely used antibiotics. Thus, it is a potential agent to combat Helicobacter pylori.


Keywords: Helicobacter pylori, Myristica fragrans, Antimicrobial resistance, Xembran
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How to cite this article:

Pankaj P. Gaonkar, A. M. Das, Maithili Rembhotkar and Amit Purnendu Goel. 2020. In-vitro Antibacterial Activity of the Product ‘Xembran®’ against Helicobacter pylori.Int.J.Curr.Microbiol.App.Sci. 9(9): 3225-3231. doi: https://doi.org/10.20546/ijcmas.2020.909.399