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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(9): 1689-1700
DOI: https://doi.org/10.20546/ijcmas.2020.909.209


Antimicrobial and Anticancer Activities of Actinomycetes Isolated from Egyptian Soils
Tarek R. Elsayed1, Diana F. Galil1, Mohammed Z. Sedik1,Hazem M.M. Hassan2, 3 , Michael R. Goharand Mahmoud W. Sadik1
1Department of Microbiology, 2Department of Biochemistry, Faculty of Agriculture,
Cairo University, Giza, Egypt
3Department of Clinical Laboratory Sciences, College of Applied Medical Sciences,
Shaqra University, Saudi Arabia
*Corresponding author
Abstract:

Actinomycetes have got considerable attention worldwide due to the production of many useful bioactive metabolites. In the present study, the antimicrobial potential of novel Actinomycetes has been evaluated by the initial screening of seven rhizosphere samples in Egypt. The primary and secondary screening were performed against Bacillus cereus (ATCC33018), and E.coli O157 (ATCC93111) as model strains of Gram positive and Gram negative species, respectively. GC-MS analysis of most active Actinomycetes extracted secondary metabolites was studied. The major compounds identified by GC-MS analysis include 2, 4-di-tert-butylphenol, 3-chloropropionic acid, heptadecyl ester, 1,2-benzenedicarboxylic acid,3-nitro, benzenepropanoic acid,3,5-bis(1,1 dimethylethyl)-4-hydroxy-, octadecyl ester, 1-monopalmitin,2TMS derivative, 1-docosene, 1-nonadecene and 1-nonacosene.


Keywords: Actinomycetes; secondary metabolites; Antimicrobial, Anticancer
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How to cite this article:

Tarek R. Elsayed, Diana F. Galil, Mohammed Z. Sedik, Hazem M. M. Hassan, Michael R. Gohar and Mahmoud W. Sadik 2020. Antimicrobial and Anticancer Activities of Actinomycetes Isolated from Egyptian Soils.Int.J.Curr.Microbiol.App.Sci. 9(9): 1689-1700. doi: https://doi.org/10.20546/ijcmas.2020.909.209