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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 9, Issue:8, August, 2020

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(8): 2092-2100
DOI: https://doi.org/10.20546/ijcmas.2020.908.238


Effect of Various Anti-mycoplasma Drugs on Haemato-biochemical Changes in Mycoplasma synoviae Infected Broilers
Vijaykumar Matham1*, A. Gopala Reddy2, Prakash Nadoor1 and M. Ramakoti Reddy3
1Department of Veterinary Pharmacology and Toxicology, Veterinary College, KVAFSU, Bidar (KS)-585401, India
2Department of Veterinary Pharmacology and Toxicology, PV Narasimha RaoTelangana State Veterinary University, Hyderabad (TS)-500048, India
3Division of Animal Health, ICAR Directorate of Poultry Research, Hyderabad (TS)-500048, India
*Corresponding author
Abstract:

The present study was conducted to evaluate the effect of various antimycoplasma drugs on haematological and biochemical changes in commercial broilers. Three hundred and twenty, day-old, unsexed broiler chicks of Vencobb strain were randomly allotted to 7 treatment groups with each treatment having 4 replicates and each replicate consisting of 10 birds. T1 served as negative control, T2-T7 groups were administered with Tylosin, Enrofloxacin, Taimulin, Erythromycin, Tilmicosin and Nizatidine whereas, T8 served as positive control group. Blood samples were collected from all the treatment groups for the estimation of haemato-biochemical profiles in mycoplasma affected broilers. Haematological examination revealed a significant increase in red blood cells, haemoglobin and packed cell volume in T7 group compared to T0. The AST levels in group T1 were significantly (p<0.05) higher as compared to group T2 and T6 but were significantly (p<0.05) lower at the end of 5th wk compared to T0. The ALT, ALP levels were significantly (p<0.05) lower at the end of 5th week in all the groups. Total protein was significantly (p<0.05) higher in T2 to T7 as compared to other groups at the end of 5th wk. All groups revealed significant (p<0.05) increase in albumin and globulin concentration on 5th week as compared to 3rd week. Thus, tylosin showed a significant restoration of haemato-biochemical parameters in Mycoplasma broilers followed by enrofloxacin, tiamulin, erythromycin, tilmicosin and nizatidine respectively.


Keywords: Mycoplasma synoviae, Broilers, Haemoglobin, Total protein, Albumin, Globulin

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How to cite this article:

Vijaykumar Matham, A. Gopala Reddy, Prakash Nadoor and Ramakoti Reddy, M. 2020. Effect of Various Anti-mycoplasma Drugs on Haemato-biochemical Changes in Mycoplasma synoviae Infected Broilers.Int.J.Curr.Microbiol.App.Sci. 9(8): 2092-2100. doi: https://doi.org/10.20546/ijcmas.2020.908.238
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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