National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Toxoplasma gondii is a protozoan that causes toxoplasmosis. Immunological status is an important factor in the course of the Toxoplasma gondii parasitic infection. This disease is often the cause of opportunistic infections that can be life-threatening in immunocompromised individuals. In immunocompromised malignancies, the risk of infection is higher than in immunocompetent individuals. The risk of infection increases when malignancy patients with chemotherapy treatment which makes the patient's immune status decrease.To determine the relationship of the type of malignancy with the incidence of toxoplasmosis in malignancy patients with chemotherapy at RSUP Dr. M. Djamil Padang.This study was an observational analytic study with a cross-sectional design by using consecutive techniques. The research started from November2019 until January 2020 in the Chemotherapy Unit and Clinical Pathology Laboratory Dr. M. Djamil Padang with a total sample of fifty-four people. The research instrument used was the Enzyme-Linked Immunosorbent Assay (ELISA) test for IgG and IgM antibodies in the blood serum of toxoplasmosis patients.The incidence of toxoplasmosis in malignancy patients with chemotherapy at RSUP Dr. M. Djamil Padang as much as 74.1 percent. According to the division of types of malignancy, toxoplasmosis was found in hematological malignancies as much as 86.7 percent and in solid malignancies as much as 69.2 percent. The significance value obtained was 0.302.The type of malignancy was not significantly related to the incidence of toxoplasmosis in malignancy patients with chemotherapy because it did not meet the p-value <0.05.
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