National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Natural components of the plants, animals and mineral sources are used as medicines since ancient time as they have fewer or no side effects, plant products have been widely used in controlling cancer as complementary to synthetic medicine is gaining increased popularity. Present study was carried out with different extract of leaf, stem, root and the whole plant of Sida cordata (burm.f.) Borss (SC) to determine their probable anticancer/ antiproliferative effect on oral cancer using Human tongue squamous cell carcinoma (CAL-27) cell lines and normal human gingival ï¬broblast (HGF) cell lines in comparison with commonly used standard drug Cisplatin. Among the various extracts used in the study, leaf extracts significantly reduced the cell viability, Highest inhibition was recorded in the ethanol extract (87.5%) followed by water (85%) at 200µg/min the MTT assay carried out. Further TUNEL assays revealed that SC extracts induces the apoptosis.
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