National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Otitis media is an inflammation of the middle ear and mastoid cavity, with recurrent ear discharge through a perforated tympanic membrane. Pseudomonas aeruginosa has been particularly blamed for deep seated and progressive destruction of middle ear structures through its toxins and enzymes. The present study was done to determine the prevalence and antibiotic susceptibility of Pseudomonas aeruginosa isolated from otitis media. Patients fulfilling clinical criteria were considered into the study. Two ear swabs were taken from each patient. Sample processing and identification of organisms was done by standard bacteriological methods as per CLSI guidelines. Antimicrobial susceptibility was done by Kirby Bauer Disk diffusion method with 12 different antibiotics for Pseudomonas aeruginosa strains. Out of 131 samples, 110 (83.97%) has shown growth of significant pathogens. Pseudomonas aeruginosa strains were isolated from 45 (38.46%) samples. The resultsof antimicrobial susceptibility testing showed maximum sensitivity to Colistin, Imipenem and Polymyxin B (100%), followed by Aztreonam (95.56%), Piperacillin-Tazobactam (93.33%), Amikacin, Ceftazidime, Cefipime, Cefaperazone-Sulbactam (84.44%), Ciprofloxacin (82.22%), Gentamicin (80%) and Levofloxacin (68.89%). Knowing the etiological agents of otitis media and their antibiotic susceptibility is of paramount importance for an efficient treatment and prevention of both disease complications and antimicrobial resistance.
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