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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Duck plague is an acute, fatal viral infection of ducks, geese, swans and other species of the order Anseriformes. The present study was undertaken for studying the immunogenicity of a wild strain of Duck Plague virus (DPV) which was adapted to grow in Chicken embryo fibroblast (CEF) cells. For this study a wild strain of DPV (DP/As-Km/0019) available in the Department of Microbiology was selected on the basis of its virulence and nucleotide homology with the vaccine strain. The selected wild strain was passaged in Chicken embryo fibroblast cell culture up to the12th passage and its immunogenicity was studied. Two groups (Group I & II) of ducklings were taken with 6 numbers of ducklings in each group. Group I was kept as unvaccinated control while Group II was used for vaccination. Significant rise in the antibody titres could be observed in Group II ducklings without producing any adverse effects. The mean antibody titres in vaccinated birds on 7th day were 16.66±2.108 with an increasing trend to 60±8.944 on 21st day and 133.33±16.865 on 30th day post vaccination respectively.