Now-a-days, many antibiotics are being used to control infectious diseases. Inappropriate use of antibiotics leads to emergence of highly resistant bacteria. The increasing resistance of microorganism to conventional chemicals and drugs is a serious global problem that has opened up the promotion research into the identification of new biocides with broad activity. Derivatives of the plants such as essential oils contain such biocides. In order to observe the anti-biofilm effect of four essential oils namely Melaleuca alternifolia (Tea tree oil), Syzygium aromatic (Clove oil), Cinnamomum zeylanicum (cinnamomum oil) and Eucalyptus globulus oil we examined these oils on Pseudomonas aeruginosa and Staphylococcus aureus. The result of this study indicates that plant extract at low concentrations may provide a complementary medication for biofilm associated infections.

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