National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Blood stream infections (BSI) are a global burden in developing countries. Increased incidence leads to morbidity and mortality in neonates as well as Paediatric age group patients. Blood culture is an effective tool for diagnosis of BSI. Aim is to determine various blood stream pathogens and their antibiotic susceptibility pattern. Blood Samples were received during February to August 2018 in JNM hospital of age group up to 12 years and incubated at BacT/ ALERT 3D System. Positives were subcultured on Blood and MacConkey agar and incubated at 37 °C for 18-24 hrs. Standard biochemical test and antibiotic susceptibility test (AST) were performed according to CLSI guidelines. Among 140 Blood samples, 73 (52.1%) were culture positive among the positive samples 36 (49.3%) in neonates, 13 (17.8%) in infants, and 24 (32.9%) in Paediatric patients. 39 (53.4 %) isolates were Gram-positive cocci (GPC) and 25 (35.6 %) were Gram-negative bacilli (GNB) and 8 (11%) were Candida spp. Among GPC, Staphylococcus aureus33 (45.83%) were predominant isolates. Out of which 14 (42.42 %) were Methicillin resistant Staphylococcus aureus (MRSA). While among GNB most frequent isolates were Pseudomonas aeruginosa 9 (12.3%) followed by Acinetobacter spp 6 (8.2%). Multi Drug Resistant (MDR) was observed in GNB. We can conclude from our study that changing trends of microbial isolates and continuous monitoring of antibiotic susceptibility pattern may help clinicians to choose wisely the empirical therapy for responsible pathogen of BSI.
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