National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Dermal health is the outcome of dynamic interactions between the microflora and immune networks to influence the health and overall wellbeing. Biophysical parameters reflect the functional integrity of skin. Biomarkers LL-37 and HBD 2, 3 have broad spectrum amino acid activity that plays role in epithelial defense system.The aim of the present work was to find out exiting correlation between the isolated genera, biophysical parameters and biomarkers of skin. Methods of isolated genera from seven cutaneous site from 45 young girls (21-22 yrs.) were ccorrelated with Biophysical parameters such as trans-epidermal water loss, epidermal hydration, skin pH, dermal health, level of biomarkers LL-37 and HBD, Meerut Institute of Engineering and Technology (MIET), Meerut. One hundred six (136) isolates presumptively identified as Staphylococcus epidermidis, Pseudomonas sp., Lactobacillus sp. Propionobacterium sp. on the basis of selective media and biochemical characterization were analyzed. Total viable count was moderately correlated with LL-37, HBD-2,3, epidermal hydration and skin gloss, bears weak positive correlation with TEWL and skin lesions and weak negative correlation with pH, redness, scales and skin integrity. The study findings suggested that areas having better dermal health are positively correlated with microbial load and biomarker LL-37 and HBD 2,3. Dermal health is a consequence of normal flora and antimicrobial peptides can be used in human skin ointments for treatment of skin disorders.
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