National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The incidence of Extended-Spectrum Beta-Lactamase Producing Enterobacteriacae (ESBL-E) infection is rising worldwide. ESBL-E is a group of pathogens increasingly encountered in ICU setting. Infections with ESBL-E are associated with increased morbidity and mortality. The present study was undertaken to determine the prevalence of patients colonized with Extended Spectrum Beta Lactamase producing Enterobacteriaceae (ESBL-E) in intensive care unit (ICU) patients and also to assess risk factors for ESBL carriage. Patients admitted or transferred to ICU were included in the study and their rectal swabs were collected on admission and discharge. The swabs were cultured and tested for ESBL-E. Out of 50 cases, 41 (82%) cases were Males and 9 (18%) cases were Females. Most of cases was in the age group of 21-30 years and above followed by that of 11-20 years. Out of these 50 cases, 29 (58%) cases were culture positive (colonised patients) and 21 (42%) cases were Culture negative (non colonised patients). Of the 29 culture-positive cases, Escherichia coli was isolated from 16 (32%) samples; Klebsiella pneumoniae was isolated from 5 (10%) samples and both were isolated from 8 (16%). The rate of subsequent development of infection was higher in colonized patients (10%) compared to non colonized patients (2%). The study revealed high rates of carriage of ESBL producers in patients admitted to the ICU. Prior colonization with ESBL-E could result in their influx and spread in ICU, challenging infection control measures. Screening of the ESBL producers in the ICU's and proper implementation of infection control measures can control the infections in ICU.
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