National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Malaria is a life-threatening parasitic disease and is a major public health problem. Considering the prevalence of malaria infection in India, there is an urgent need to look for tests that are simple, inexpensive and can be used to improve diagnosis, so that accurate treatment and management can be done. Present study was undertaken to compare and study the efficacy of peripheral blood smear (PBS), modified centrifuged buffy coat smear (CBCS) and rapid malaria antigen detection test (RDT) in malarial diagnosis. The study included all cases with fever for >24 hours. Patients who came for follow up visit of an earlier episode of malaria or within 4 weeks of post treatment were excluded. For statistical analysis of results, RDT was used as gold standard. Highest number of cases were detected by RDTs (97.83%) followed by CBCS (91.30%). PBS was found to be a better test to diagnose malaria than RDT. CBCS were found to be of less utility in diagnosing malaria as compared to RDT. CBCS would be especially useful with negative or low parasitic index (PI) which may be missed by the conventional PBS. Hence, present study concludes that, the CBCS method can be adopted in the routine as it just needs an additional centrifugation procedure to the conventional method making PBS. Key words Malaria, Peripheral blood smear, centrifuged buffy coat smear, Rapid malaria antigen detection test
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