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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 8, Issue:7, July, 2019

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(7): 2794-2799
DOI: https://doi.org/10.20546/ijcmas.2019.807.349


Klebsiella pneumoniae: Prevalence of ESBL Producing Clinical Isolates and their Antimicrobial Susceptibility Pattern in a Hospital Setting
B. Sandya Gnana Sailaja and A. Heraman Singh*
Department of Microbiology, GSL Medical College, Rajahmundry - 533296, India
*Corresponding author
Abstract:

The incidence of infections caused by multidrug resistant ESBL producing K.pneumoniae is on rise. The treatment of these infections have become increasingly difficult and life threatening. Knowledge on prevalence of these infections and corresponding antimicrobial susceptibility patterns is essential regionally. Routine standard operative procedures were followed in the laboratory in processing the clinical specimens for culture and sensitivity. ESBL producing K.pneumoniae were identified by phenotypic combination disc test. Majority of K.pneumoniae were isolated from respiratory specimens and pus, followed by urine and blood respectively. 42 (40.38%) isolates were confirmed as ESBL producing K.pneumoniae. The resistance demonstrated to 3rd generation cephalosporins was significant and to non β lactam antibiotics was moderate. Resistance exhibited to piperacillin/tazobactam was low and nil to carbapenems. The infections caused by multidrug resistant ESBL producing K.pneumoniae are significant. Due to their multidrug resistant nature the treatment options available are limited. Therefore, active surveillance and appropriate infection control measures are necessary to control the spread of these pathogens.


Keywords: ESBL producing K.pneumoniae, cephalosporins, piperacillin/tazobactam, carbapenems

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How to cite this article:

Sandya Gnana Sailaja, B and Heraman Singh, A. 2019. Klebsiella pneumoniae: Prevalence of ESBL Producing Clinical Isolates and Their Antimicrobial Susceptibility Pattern in a Hospital Setting.Int.J.Curr.Microbiol.App.Sci. 8(7): 2794-2799. doi: https://doi.org/10.20546/ijcmas.2019.807.349
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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