Fungal phytopathogens are causes of many plant disease and maximum loss of crop yields, especially in tropical regions. Chemical fungicides are extensively used in agriculture. However, these products may cause problems such as environmental pollution and affect human health, microorganism particularly fungi as biocontrol agents have high potential to control plant disease and eco-friendly without side effect on the environments. In the present investigation suggests that the antagonistic activity of some potential soil fungi against brown leaf spot pathogen Bipolaris oryzae were studied in in vitro experiment. The maximum potential soil fungi showed the ability to inhibit the pathogen in a broad aspects and the mechanism of the interaction studies were discussed.

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