National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The objective of this study was to perform antibacterial activity of soap containing hexane extract of leaves of Morinda morindoides (Baker) Milne-Redh (Rubiaceae) codified "MORINDA" against Staphylococcus aureus and Pseudomonas aeruginosa. This soap was developed by incorporation hexane extract of M. morindoides as antimicrobial agent in formula of basic soap (soap without extract). Minimum inhibitory and bactericidal concentrations (MIC and MBC) of soap "MORINDA" and basic soap against the two above bacteria strains were determined by agar both dilution and plate methods. The results showed high bactericidal activity of soap "MORINDA" against two strains tested with same values of MIC and MBC of 31.25 mg/mL. Basic soap presented the lower bactericidal effect with MIC of 62.50 mg/mL for the two strains tested and MBC of 125.00 mg/mL and 62.50 mg/mL respectively for S. aureus and P. aeruginosa. Comparatively to control soap, hexane extract of M. morindoides gave to soap "MORINDA" effectiveness bactericidal power against these two bacteria involved in cutaneous infections. This study corroborate our previous investigations which showed antifungal activity of this soap and high antibacterial activity of hexane extract of M. morindoides.
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