National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Among the non-tuberculous causes of meningitis, cryptococcal meningitis tops the list with prevalence around five percent in India. The present study was carried out to compare latex agglutination test with India Ink Preparation and fungal culture admitted to a tertiary care hospital. The samples for the study were received from all age groups of HIV-positive patients suspected of having meningitis admitted to either medicine or paediatric ward and HIV-negative patients with signs and symptoms of meningitis were taken as control group. Out of 1,224 HIV-positive patients, 224 were clinically suspected cases of meningitis. Antigen detection test was done on 160 patients irrespective of their HIV status. Of these, 22 cases were found to be positive for the cryptococcal antigen detection test; only 18 cases were culture positive and the remaining four (2.82%) were culture negative. Majority (18, 81.8%) of the HIV-positive patients with cryptococcal meningitis, had CD4+ T-lymphocyte cell count < 200 cells/ µl. It was observed that cryptococcal antigen detection test was more sensitive (100%) as compared to culture (81.8%) and India ink preparation (68.2%).
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