National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The usefulness of Rapid test and ELISA in the diagnosis of HCV in haemodialysis patients was analysed. In this study, Immuno Chromatography Test [ICT] rapid test was compared with ELISA for the effective detection of anti-HCV antibodies in patients on haemodialysis. A total of 106 blood samples, from chronic renal disease patients on haemodialysis were taken from the Department of Nephrology, Government Medical College Hospital, for a period of six months from July to December 2011. Sera were tested for anti HCV antibodies by rapid ICT and further tested by third generation ELISA. Anti-HCV antibodies were positive in 6 (5.66%) patients by ICT method while 7 (6.6%) patients were positive by ELISA method. The sensitivity and specificity of the ICT kit were 85.7% and 100% respectively whereas positive and negative predictive values were 100% and 99% respectively, which were significantly high and quite equivalent to the ELISA results. An ideal rapid test is a boon in time-saving situations like dialysis. Hence we conclude that HCV screening can be preferably done by a rapid test followed by a supplemental ELISA and polymerase chain reaction.
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