National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Dengue is the most critical arthropod borne viral infection and a major public health concern globally in recent years infecting about 50 million people each year. Dengue infected patients present with symptoms varying from mild fever to life threatening shock. Associated thrombo cytopaenia is a hall mark of a life threatening dengue infection. A platelet count of less than 100,000/µl is a diagnostic criteria for dengue haemorrhagic fever (DHF) as per World Health Organization (WHO) guidelines, 2015. Thrombocytopaenia can be seen in both dengue fever (DF) and DHF. In this study, a total of 1228 patients both out patients and inpatients of Akash Hospital in Bengaluru rural were screened for dengue infection. A rapid-Immuno chromatographic test, (ICT) SD Bioline Dengue Duo® was used to run all the samples for detection of NS1antigen (nonstructural protein), IgM (immunoglobulin M) and IgG (immunoglobulin G). NS1 antigen is an early diagnostic marker, appears on the first day of fever. All positives were confirmed by using Bhat Bioscan® Dengue rapid test kit also detects NS1antigen, IgM and IgG. Out of 1228 samples 324 samples were seropositive. Platelet counts were performed on whole blood on these seropositive patients using Sysmex XS 800i automated haematology analyser. Among the 324 seropositive patients, 17(5.24%) had severe thrombocytopaenia, 109 (33.64%) were showing moderately low platelet count, 93(28.70%) with a borderline count and 105 (32.40%) had a normal platelet count.
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