Bacterial infections and antibiogram in device associated infections in MICU, ICU of hospital. The study was carried during the period of Jan 2017 to Dec 2017 in Bacteriology section department of Microbiology in Government Medical College and hospital Aurangabad. 530 samples received from patients of ICU and MICU of hospital for culture and sensitivity. Out of which 330/530 (62%) samples were from endotracheal secretions suspected of pneumonia and 90/530 (17%) were Urine samples and 75/530 (14%) were blood samples. Samples were processed identified by different biochemical reactions. Only device associated hospital acquired infection were studied. Out of 330 samples of ventilated associated pneumonia 199 (60%) showed bacterial growth 131 samples were sterile. In 90 urine samples 34/90 (38%) samples showed growth and 56 were sterile. In 75 blood samples 22/75 (29%) samples showed growth and 43 samples were sterile. In this cases pattern of microorganisms were identified with assessment of antibiotic sensitivity profile. The common infection found was ventilated associated pneumonia followed by Urinary tract infection and blood stream infections. Organisms isolated were Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumanii, Escherichia.coli, Enterobacter and Staphylococcus aureus. Gram negative bacteria isolated were in maximum numbers as compared to gram positive cocci. Antibiotic sensitivity pattern of these isolates was done against commonly used antibiotics. Multidrug resistance pattern was noted. Patients admitted in MICU and ICU are more susceptible to Hospital acquired infections. In spite of antibiotic treatment, occurrence of Hospital acquired infections is responsible for increased stay of patients in hospital. Among Hospital acquired infections common Ventilator associated pneumonia, urinary tract infection and blood stream infections. Gram negative bacilli were seen in more numbers than in gram positive cocci.  Organisms were showing multidrug resistance pattern. Association of ventilator associated pneumonia were common occurrence followed by Urinary tract infection and blood stream infection. Gram negative bacilli of Enterobactericiae were common isolation. Multidrug resistance to antibiotics was noted.

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