National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
UTI is one of the most common infectious diseases in people of all age groups from the neonates up to geriatric age groups and geographical locations are affected and thus represent a major source of human discomfort. Since the mid 1990’s, hospital-associated Enterococcal bacteriuria, has shown a significant increase in frequency over time and is the second most frequently isolated urinary pathogen. Enterococcus faecalis is more common in nosocomial infections than E. faecium, but E. faecium has a great ability to acquire drug resistance. The present study was planned to determine the antimicrobial susceptibility pattern of urinary isolates of Enterococcus species and the emergence of vancomycin resistance and high level aminoglycoside resistance. A total number of 187 urinary isolates of enterococci were tested for phenotypic characteristics by conventional methods and growth on hicrome UTI agar. Antimicrobial susceptibility pattern was studied by Kirby-bauer disk diffusion technique, screening agar method and minimum inhibitory concentration (MIC) testing by E test to determine vancomycin resistance. Out of 187 enterococcal isolates, 149 (79.67%) were Enterococcus faecalis and 38 (20.32%) were Enterococcus faecium. Among predisposing factors in the present study, catheterization was found to be the most important predisposing factor where the highest number of patients (43.89%) had enterococcal UTI, followed by diabetes accounted for 31.23 %. 13 enterococcal isolates were resistant to vancomycin by E test and all the isolates were susceptible to teicoplanin, linezolid and tigecycline. Maximum resistance was observed against high level amino glycoside (HLAR), i.e.50.8%. Followed by, most of the isolates were resistant to tetracycline and ampicillin, i.e 44.3% and 42.7% respectively. Multidrug resistant enterococci especially resistant to vancomycin and aminoglycosides have become a threat to patient's safety, making it a formidable nosocomial pathogen.
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