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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
A comparative study on the anticancer effects of anthocyanins derived from banana cv. Nendran flower bracts against human colon (HT-29) and cervical cancer (HeLa) cells were investigated. In vitro assays by MTT, AO/EtBr and MMP revealed that anthocyanins extract inhibited the growth of both HT-29 and HeLa cells. The percentage of cell viability decreased linearly with increment of anthocyanins. The IC50 values for anthocyanins were 41.18 µg/ml for colon cancer cells and 46.50 µg/ml for the cervical cancer cells by MTT assay. The MMP assay indicated IC50 values of 71.18 and 106.5 µg/ml respectively for HT-29 cells and HeLa cells. The study demonstrates that anthocyanins of banana flower bracts are potential anti-cancerous compounds.