National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The acquisition of metallo-β-lactamases (Carbapenemase) by Gram Negative Bacteria has recently emerged as one of the most worrisome resistance mechanisms, a virtue by which they can hydrolyze all beta-lactam antibiotics including penicillins, cephalosporins and carbapenems. This study was undertaken for phenotypic detection of Carbapenamase in Gram Negative Bacteria by Modified Hodge Test. A total of 200 isolates of Gram Negative Bacteria recovered from various clinical specimens. They were subjected to antimicrobial sensitivity testing and Modified Hodge Test. It was found that 46 isolates of Gram Negative Bacteria showed Carbapenamase production by Modified Hodge Test out of which 29 isolates were resistant of Carbapenems by disc diffusion. However the remaining 17 isolates could be potential Carbapenamase producers and may lead to treatment failure. Hence it is necessary to carry out Modified Hodge Test for Gram Negative Bacteria.
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