|
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Propolis had been well documented in traditional medicine for treating systemic immune diseases, allergic diseases, viral diseases and organ-specific inflammatory diseases since more than one thousand years. During the last ten years, immunoregulatory and anti-inflammatory properties of propolis have been published. The therapeutic characteristics of propolis have been well known for a very long time. It has been used in folk medicine for different nations as early in Egypt as 3000 BC. In recent years, propolis has become a subject of increasing interest for chemists and biologists. It had various biological and therapeutic activities. In in vitro and in vivo assays provided new information concerning its mechanisms of action. Propolis possesses variable biological activities activity was investigated on antiviral, antibacterial, fungicidal, anti-inflammatory, antitumor, antiparasitic, antioxidant, cytokines and immune response. Immunomodulatory and antitumor properties, considering propolis effects on antibody production and on different cells of the immune system which involving the innate and adaptive immune response. This review was aimed to through more light on the enhancing activity of propolis on immune response, and opens a new perspective on the investigation of propolis biological properties on immune mechanism.