Transgenesis in Animals: Principles and Applications – A Review

Sheikh Firdous Ahmad; Kanika Mahajan; Tania Gupta; Maliha Gulzar; V

doi:https://doi.org/10.20546/ijcmas.2018.710.358

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Original Research Articles Volume : 7, Issue:10, October, 2018

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Int.J.Curr.Microbiol.App.Sci.2018.7(10): 3068-3077

DOI: https://doi.org/10.20546/ijcmas.2018.710.358

Transgenesis in Animals: Principles and Applications – A Review

Sheikh Firdous Ahmad^1*, Kanika Mahajan², Tania Gupta³, Maliha Gulzar⁴ and Vandana Yadav⁵

¹Division of Animal Genetics, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly (UP) - 243 122, India
²Division of Livestock Products Technology, FVSc & AH, SKUAST-J, Jammu - 180 009, India
³Department of Veterinary Microbiology, Dr GC Negi College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh - 196 062, India
⁴Department of Veterinary Public Health, FVSc & AH, SKUAST-K, Shuhama, Srinagar, J&K - 190 006, India
⁵Animal Genetics & Breeding Division ICAR-National Dairy Research Institute Karnal, Haryana - 132 001, India

^*Corresponding author

Abstract:

Transgenesis refers to the technique involving the manipulation of genes of one organism and deliberate addition into the genome of another organism of same or other species and sometimes specific inhibition of endogenous gene inhibition. Transgenesis promises to solve different problems. The animals produced through the process of transgenesis will serve us various purposes from medicinal to commercial uses. Different methods of producing transgenic animals are available; however, their effectiveness varies with species involved. Various kinds of transgenic animals have been produced to date. However, few issues related to ethics and regulations of transgenic animals remain to be addressed. In this review, we tried to cover the basics of transgenics to understand their promise in the livestock world.

Keywords: Ethics, Regulation, rDNA, Transgene, Xenotransplantation

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How to cite this article:

Sheikh Firdous Ahmad, Kanika Mahajan, Tania Gupta, Maliha Gulzar and Vandana Yadav. 2018. Transgenesis in Animals: Principles and Applications – A Review.Int.J.Curr.Microbiol.App.Sci. 7(10): 3068-3077. doi: https://doi.org/10.20546/ijcmas.2018.710.358

Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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Original Research Articles Volume : 7, Issue:10, October, 2018

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