International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 7, Issue:9, September, 2018

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(9): 3464-3470

Serum Tumor Necrosis Factor-Alpha (TNF-α) Levels in Children with Nephrotic Syndrome and Its Correlation with Biochemical Parameters
Ammar B. Al-Assadi1, Nidhal A. Mohammed1 and Shatha H. Ali2
1College of Biotechnology, Al-Nahrain University, Iraq
2College of Medicine, Al-Nahrain University, Iraq
*Corresponding author

The aim of this study is to compare the levels of TNF-α in children with nephrotic syndrome and healthy control children and the correlation of TNF-α with clinical feature of NS. Fifty children with NS were divided into four groups: 14 steroid sensitive infrequent relapse (SSIFR), 12 steroid sensitive frequent relapse (SSFR), 9 steroid resistance (SR) and 15 newly diagnosis (ND) compared to twenty-five unrelated healthy children. The serum IL-13 levels for NS patients and healthy control children were measured by R&D quantitative ELISA kit. Serum levels of TNF-α showed highly significant difference between patients with NS (15.68 ± 2.38pg/ml) and healthy control (1.066 ± 0.65pg/ml), and there is no significant different among NS groups. Highly significant correlation between TNF-α mean level and biochemical markers of NS patients also reported in this study.


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How to cite this article:

Ammar B. Al-Assadi, Nidhal A. Mohammed and Shatha H. Ali. 2018. Serum Tumor Necrosis Factor-Alpha (TNF-α) Levels in Children with Nephrotic Syndrome and Its Correlation with Biochemical Parameters.Int.J.Curr.Microbiol.App.Sci. 7(9): 3464-3470. doi:
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