International Journal of Current Microbiology and Applied Sciences |
ISSN: 2319-7706 Volume 2 Number 8 (2013) pp. 177-186 |
Antimicrobial chemotherapy for microorganisms causing male infertility |
S.Sasikumar1
*, E.K.Madhankumar1
, D.Dakshayani1
, A.Franklin2
and Rajkumar Samuel |
1Nova IVI fertility centre, RA.Puram, Chennai, Tamilnadu, India 2Sri Lakshmi Narayana Institute of Medical Sciences, Puducherry, India 3Hubert Enviro Care Systems (P) Ltd, Chennai, Tamil Nadu, India *Corresponding author e-mail: sasikumarsundararajan1@gmail.com |
A B S T R A C T |
Many studies have been performed to examine the effect of semen bacterial
infection on the outcome of IVF. The presence of bacteria wanted treatment by
antibiotics due to possible adverse effects on semen parameters. Complications arise when determining which bacteria are significant and which merely represent skin contamination. When examining statistics or all patients which positive
semen culture. At the time of IVF , it was found no difference in the pregnancy
rate when compared with patient with negative culture. It was the notion that bacteria may have an adverse effect on semen parameters and on IVF results. Staphylococcus aureus was the highest prevalent bacteria in the study. Other
isolates including Escherichia coli, Klebseilla ozaenae, Proteus vulgaris Pseudomonas aeruginosa also recovered from the semen. These all have been
reported to possess invitro spermicidal activity.Antibiotic sensitivity for the
isolated organism shows their sensitivity on the antibiotics. The highly sensitive
antibiotics were identified Vancomycin, Gatifloxacin, cefoperazone / Sulbactum, Amikacin, Imipenum. Minimum inhibitory concentration of thse antibiotics also
determined for the better treatment to the IVF patients. |
Keywords |
IVF; semen parameters; Klebseilla ozaenae; Klebseilla ozaenae; Proteus vulgaris; Pseudomonas aeruginosa; Escherichia coli |