Sperm Transcriptomics: An Emerging Technique to Assess Male Fertility

Kennady Vijayalakshmy; Dharmendra Kumar; Meenakshi Virmani; Ninan Jacob; Pradeep Kumar

doi:https://doi.org/10.20546/ijcmas.2018.709.141

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Original Research Articles Volume : 7, Issue:9, September, 2018

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Int.J.Curr.Microbiol.App.Sci.2018.7(9): 1188-1200

DOI: https://doi.org/10.20546/ijcmas.2018.709.141

Sperm Transcriptomics: An Emerging Technique to Assess Male Fertility

Kennady Vijayalakshmy^1*, Dharmendra Kumar², Meenakshi Virmani³, Ninan Jacob¹ and Pradeep Kumar²

¹Department of Veterinary Physiology, Rajiv Gandhi Institute of Veterinary Education and Research, Kurumbapet, Puducherry-605 009, India
²Department of Animal Physiology and Reproduction, ICAR-Central Institute for Research on Buffaloes, Hisar-125004, Haryana, India
³Department of Veterinary Physiology, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar-125004, Haryana, India

^*Corresponding author

Abstract:

Semen sample has to be analyzed to determine the fertilization capacity of sperm. This helps in the efficient use of semen sample for cryopreservation and their further use in artificial insemination. The current methods used to analyze semen just indicate a predictive fertility status, not an actual fertilization capacity. Certain mRNA population / transcripts which are present in spermatozoa are found to have a potential role in fertilization capacity. The analysis of mRNA population in sperm by means of isolation of RNA from sperm and profiling of these mRNA transcripts may give the actual fertilization status of the sperm. This technique is non- invasive in nature and it can be used as promising technique to screen the fertility of male animals at an early stage.

Keywords: Fertility markers, Male infertility, Semen, Sperm mRNA, Transcriptome analysis

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How to cite this article:

Kennady Vijayalakshmy, Dharmendra Kumar, Meenakshi Virmani, Ninan Jacob and Pradeep Kumar. 2018. Sperm Transcriptomics: An Emerging Technique to Assess Male Fertility.Int.J.Curr.Microbiol.App.Sci. 7(9): 1188-1200. doi: https://doi.org/10.20546/ijcmas.2018.709.141

Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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Original Research Articles Volume : 7, Issue:9, September, 2018

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