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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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Original Research Articles                      Volume : 5, Issue:10, October, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(10): 261-266
DOI: http://dx.doi.org/10.20546/ijcmas.2016.510.029


Gold Nanoparticles for Photothermal Therapy of Cancerous Cells in vitro
Sumaiah I. Hussein1*, Ali S. Sultan2 and Nahi Y. Yaseen
1Department of Basic Science, College of Dentistry, Baghdad University, Iraq
2Department of Biology, College of Science, AL-Mustansiriya University, Iraq
*Corresponding author
Abstract:

Cancer continues to be among the leading causes of death worldwide. The use of nanomaterials is becoming increasingly common in the medical application field, especially in cancer diagnosis and therapeutic. This study was done to evaluation the efficacy of photothermal therapy by using gold nanoparticles with laser irradiation on two cancer cell lines in vitro, HeLa (human cervicle cancer cell line) and AMN3 (mammary adenocarcinoma), in addition, use gold nanoparticles alone, for comparison between them. The results shows that photothermal therapy more effect than gold nanoparticles alone on cancer cells, as well as AMN3  more affect than HeLa cell line, so the effect is related to type cell line, concentration, incubation period and size of particles. The present study suggests that photothermal therapy by gold nanoparticles is a good candidate for medical application as anticancer in future.


Keywords: GNPs,PTT,Cancer cells,in vitro HeLa.

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How to cite this article:

Sumaiah I. Hussein, Ali S. Sultan and Nahi Y. Yaseen. 2016.  Gold Nanoparticles for Photothermal Therapy of Cancerous Cells in vitro.Int.J.Curr.Microbiol.App.Sci. 5(10): 261-266. doi: http://dx.doi.org/10.20546/ijcmas.2016.510.029
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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