National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The increasing prevalence of infections caused by antibiotic-resistant bacteria makes empirical treatment of these infections difficult. We studied prevalence of ESBL and Amp C beta lactamases in 241 uropathogens and compare the antibiotic susceptibility pattern in them. In our study E coli was most common pathogen followed by pseudomonas, klebsiella. ESBL was produced by 38.58, Amp C by 12.03% and both type beta lactamases present in 3.37%. There is significant difference in antibiotic susceptibility of ESBL producing and non producing strains ESBL and Amp C producing isolates are less susceptible to commonly used antibiotics there is significant difference in their susceptibility except Nitrofurantoin difference is not significant (p value is <0.05) which is oldest drug, now it is commonly not uses to treat UTI. Resistance to Amikacin was found to be comparatively lower in both ESBL and non-ESBL producers. Gentamicin, Chloramphenicol and Cotrimoxazol were found to be more effective on non-ESBLs as compared to ESBL producing uropathogens.
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