National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
In this study cytotoxic effect of kaempferol isolated from Vigna unguiculata was evaluated on breast cancer (MCF-7) and lung cancer A459 cell lines. MCF-7 and A459 cells were cultured in DMEM medium and incubated with different concentrations (100, 50, 25, 12.5, 6.25 µg/ml) of kaempferol .The cell viability was assessed by MTT assay. Kaempferol has decreased malignant cells in a concentration dependent manner. The IC50 values in MCF-7 and A459 cells were determined as 90.28 ± 4.2 µg/ml and 35.80 ± 0.4 µg/ml respectively. It may be concluded that kaempferol can cause cell death in MCF-7 and A459 cancer cells which is considered as a promising chemotherapeutic agent in breast cancer and lung cancer treatment.
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