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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The present work was designed to investigate the toxic impacts of silk dye waste effluent induced on the histopathology of the heart tissue in the Swiss albino male mice Mus musculus and their mitigation using by Moringa oleifera leaf extract. Five sets of animals i.e. Group-I (Control), Group-II (fed with 50% silk dye), Group-III (fed with 100% silk dye), Group-IV (mice fed with 50% dye treated with M. oleifera leaves powder), Group-V (mice fed with 100% dye treated with M. oleifera leaves powder) have been taken for experiment. The dose of silk dye was 2ml/day to both groups-II and III and M. oleifera leaf is given as per the standard dose (300mg/kg b.w) to both animals of group IV and V. The result was demonstrated when treated with silk dye waste showed some changes including blood vessels degeneration, disrupted endocardium, myocardium, epicardium and collagenous fibers thickness but their mitigation using Moringa oleifera leaf powder. These results, along with previous observation, suggest that M. oleifera may be useful in cardiac tissues damage that is a result of silk dye waste effluent toxicity.