National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The aim of our study was to examine the changes in the trend of antibiotic resistance of organisms from urinary tract infection over a five-year period in our hospital. The data selected were all urine cultures from the hospital urine samples over a five-year period. Results of urine cultures from patients throughout the hospital were analysed and information on susceptibility to four antibiotics i.e., Gentamycin, Amikacin, Ciprofloxacin and Nitrofurantoin was collected. Total number of urine samples in the study period were 15949, out of which 5690(35.67%) showed the growth of bacteria with significant count. E. coli was the commonest organism isolated followed by Klebsiella spp., Pseudomonas, S. aureus and others. Ciprofloxacin resistance has been increasing since past five years (2012 -33% and 2016-40%),and even gentamycin resistance has increased since past five years in (2012-31% and 2016-33%) also statistically amikacin show rise in resistance pattern(2012-31% compared to 2016-36%)As resistance to nitrofurantoin is less compared to other drugs i.e., (2012-14% and in 2016-17%). Nitrofurantoin resistance is low compared to other drugs. It is both cost effective and efficacious for empirical treatment of uncomplicated UTIs therefore should be considered the mainstay of treatment of uncomplicated UTIs. This can be switched to targeted therapy on the basis of definitive subsequent culture and AST results.
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