National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Hematological changes are among the most common complications encountered in malaria. This study analyzes and statistically evaluates the hematological changes occur in complicated malaria as compared to uncomplicated malaria. The present study was conducted from January to December 2012 in SCB Medical College, Cutack of Odisha. A total of 120 severe/ complicated malaria patients and 80 uncomplicated malaria patients were investigated. The complicated malaria cases had significantly low level of Hb level as compared to uncomplicated cases (P<0.05). Hyperparasitemia (>250000/µl) was found in 25 cases, leukocytosis (>10 x 109 /L) in 34 cases, leukopenia (<4x109 /L) in 18 cases, thrombocytopenia (< 60 X 10 9 /L) in 34 cases and overt bleeding was observed in 54 cases having complicated malaria. Atypical lymphocytes were present in 4 cases while at least 36 of cases had malarial pigment in monocytes and 4 cases in neutrophil. The patients having complicated malaria had significantly low platelet count compared to uncomplicated malaria. Around 79.63% cases showed a significantly high level of PPT and 53.70% with high aPTT (p<0.05) than uncomplicated cases. The increased plasma d-DIMER level was significantly high in complicated cases as compared to uncomplicated cases (40%). This study revealed that routinely used haematological findings such as hemoglobin, hyperparasitemia, thermbocytopenia, platelet count, PPT level, aPPT and d-DIMER can be considered as prognostic marker for severe/ complicated malaria in endemic areas
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