National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Malaria diagnosis is relatively easy, but making the blood film is still an obstacle in the field because it is invasive, requires expertise, and increases the risk of transmission of infectious diseases. Antigen detection of several microorganisms in saliva, the opportunity to make saliva as an alternative diagnostic specimen for malaria. This study examines the presence of malaria parasites PfHRP-2 antigen in saliva. Saliva was collected from falciparum malaria patients in some health centers in West Sumatra. PfHRP-2 antigen was examined by ELISA using a kit called CELISA antigen. PfHRP-2 antigen detection in saliva specimens was evaluated in the presence of Plasmodium falciparum on blood film as a gold standard. Out Of the 64 patients whose positive Plasmodium falciparum was confirmed by microscopy, 63 people tested positive for PfHRP-2 antigens by ELISA on blood specimens, and 32 were positive in saliva. PfHRP-2 antigens were not found in all the negative controls. Saliva can be used as a specimen for the detection of PfHRP-2 antigen. Development of detection methods necessary for the saliva specimens useful for malaria diagnosis.
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