|PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
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Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38
Bacterial microflora of fishes is part of a complex ecosystem responsible for a variety of diseases in fish and man. A survey was conducted to determine the occurrence and antimicrobial susceptibility of microorganisms from the gastrointestinal tract of 220 fishes belonging to two specie Clarias gariepinus and Heterobranchus species. A total of 5 bacterial species were identified and their prevalences were: Escherichia coli 16 (36.60%), Proteus vulgaris 10 (22.70%) Salmonella typhi 4 (9.09%), Staphylococcus aureus 8 (18.80%) and Staphylococcus epidermidis 6 (13.63%). Antibiotic susceptibility by differential standardized disc method showed high incidence of resistance to cotrimoxazole, streptomycin and tetracycline as well as a low resistance to ciprofloxacin, sparfloxacin and pefloxacin by the isolated organisms. Statistical analysis showed that there was significant positive association between the prevalence of isolates and their susceptibility to the various antibiotics (X2=72.12; p<0.05 and p=0.00). This findings dissipated array of microbial isolates and the sensitivity and resistant patterns of the isolates to a variety of antimicrobial agents. The difference in the sensitivity of the isolates to a variety of antibiotics as observed in this study could be attributed to strain or specie differences, and also the usage, misuse or abuse of these drugs coupled with prolonged antibiotic therapy which has favored the emergence of resistant strains. There is need for rational approach in monitoring of microorganisms and their sensitivities to control these diseases in the human population.