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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2015 - IJCMAS--ICV 2015: 85.95 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2017) [Effective from January 1, 2017]For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2015: 85.95
Index Copernicus ICI Journals Master List 2015 - IJCMAS--ICV 2015: 85.95
For more details click here
journals IJCMAS
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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(4): 2298-2302
DOI: https://doi.org/10.20546/ijcmas.2017.604.268


The Efficacy of Various Anti- Rabies Vaccines in Dog Bite Victims in Tuticorin and Bangalore, India
Gifty Immanuel1,2* and S. Shanmugavel3
1Infectious Diseases Physician, CSI Hospital Bangalore-560005, India
2Center for AIDS and Antiviral Research, Tuticorin-628003, India
3Department of Zoology, V.O.C College, Tuticorin-628008, Tamilnadu, India   
*Corresponding author
Abstract:

To determine the most effective vaccine against rabies infection in the vaccines who took different types of vaccines for dog bite in rural areas of Tuticorin and urban areas of Bangalore. All the blood samples collected post intramuscular vaccinations were tested by RFFIT (Rapid Fluorescent Focus Inhibition Test). A total of 100 blood samples from vaccines were collected twice on days (14, 28) from volunteers in the period between 2013-2016. A cohort of 25 vaccinees were assigned to four different types of rabies vaccines groups PCEV (Rabipur, India), PVRV (Verorab, France), HDCV (Mireux, France), PDEC (Vaxirab, India). Responses to four commercially available vaccines in India were compared namely PCEC, HDCV, PVRV, PDEV. Although all available types of vaccines had elicited the required minimum rabies virus neutralizing antibody RVNA (titers above 0.5 IU), the following vaccine Purified Vero Cell Vaccine PVRV elicited the maximum neutralizing antiviral antibodies in the vaccine recipients (vaccinees). However, no significant differences in the quantum of RVNA were observed in all groups.


Keywords: Rabies, Vaccinees, Zoonosis, Immunity, Prophylaxis, Neutralizing antibody.
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How to cite this article:

Gifty Immanuel and Shanmugavel, S. 2017. The Efficacy of Various Anti- Rabies Vaccines in Dog Bite Victims in Tuticorin and Bangalore, IndiaInt.J.Curr.Microbiol.App.Sci. 6(4): 2298-2302. doi: https://doi.org/10.20546/ijcmas.2017.604.268