|PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
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Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38
Diabetes is a metabolic disorder due to insufficiency of insulin (absolute/relative) and generally classified as IDDM and NIDDM. Present study was conducted to observe the anti-diabetic effect of Morinda citrifolia fruit juice. 48 wistar rats of either sex comprising of four groups were taken for the study. Three groups of 36 rats was induced diabetes with single i/p administration of 5% w/v of alloxan monohydrate in normal saline. One group was kept as healthy control (Group-I) and one as diabetic control (Group-II).For comparison of the effect of Morinda citrifolia fruit juice @ 2 mg/kg Bwt. (Group-IV) with normal standard drug i.e. metformin @ 100 mg/kg Bwt. (Group-III). All the treatments were given through oral route. Parameter studied were serum Glucose, Triglyceride, Total cholesterol, HDL, LDL and Haemoglobin at 1st, 14th, 28th days after commencement of treatment. After induction of diabetes serum glucose and triglyceride concentration increased and total cholesterol, HDL, LDL concentration decreased at statistically significant level where as there was no statistical change in haemoglobin level. The group treated with Morinda citrifolia fruit juice showed better result but the best result was obtained with the standard anti-diabetic drug.