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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2015 - IJCMAS--ICV 2015: 85.95 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2017) [Effective from January 1, 2017]For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2015: 85.95
Index Copernicus ICI Journals Master List 2015 - IJCMAS--ICV 2015: 85.95
For more details click here
journals IJCMAS
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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(4): 906-917
DOI: https://doi.org/10.20546/ijcmas.2017.604.115


Diagnosis of Bacterial Vaginosis among Symptomatic Egyptian Women: Value of Assessing Bacterial Sialidase Activity
Fatma AL-Zahraa M. Gomaa1, Hala M. Hafez2*, Ahmed Al Anwar3 and Noureen I. El-Metwally1
1Microbiology and Immunology Department, Faculty of Pharmacy, Al-Azhar University, Egypt 2Clinical Pathology Department, Faculty of Medicine, Ain Shams University, Egypt 3Gynaecology and Obstetrics Department, Faculty of Medicine, Ain Shams University, Egypt
*Corresponding author
Abstract:

The development of point-of-care tests that are accurate, simple, rapid, low cost, and that do not require high levels of training for their interpretation is integral to improving the syndromic management algorithms for vaginal discharge that at present perform poorly. The present study aimed at evaluating the usefulness of assessing the bacterial sialidase activity as a rapid, sensitive and specific alternative compared to routine diagnostic methods for diagnosis of bacterial vaginosis (BV). The study included 50 female patients presenting with excessive and/or abnormal vaginal discharge. Four swabs were used to collect the vaginal discharge from each patient and were examined by culture, Amsel's criteria, Gram stain using the Nugent's score and BVBlue test to assess the sialidase activity. BV was detected in 18% of the studied women by all of the diagnostic methods. Compared to Nugent's score ?7, the detection of sialidase by BVBlue test had 100% sensitivity and 84.6% specificity. There was a good agreement between the results of BVBlue test and clinical diagnosis using Amsel's criteria. We concluded that the determination of sialidase activity by BVBlue test can be a simple, rapid, and sensitive alternative to routine diagnostic methods that require expert manpower and sophisticated techniques.


Keywords: Vaginosis, BV, Sialidase, BVBlue, Nugent
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How to cite this article:

Fatma AL-Zahraa M. Gomaa, Hala M. Hafez, Ahmed Al Anwar, Noureen I. El-Metwally. 2017. Diagnosis of Bacterial Vaginosis among Symptomatic Egyptian Women: Value of Assessing Bacterial Sialidase Activity.Int.J.Curr.Microbiol.App.Sci. 6(4): 906-917. doi: https://doi.org/10.20546/ijcmas.2017.604.115