|PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : email@example.com / firstname.lastname@example.org
Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38
Pregnant women in India belonging to low socio-economic group are exposed to a variety of infections due to poor hygiene and environment. Though placental barrier prevents some microbes crossing from maternal into fetal circulation, TORCH agents cross the barrier and result in various clinical conditions. Objectives of the study are to study the seroprevalence of TORCH infections in pregnant women with Bad obstetric history (BOH) and also to know the outcome of these infections in newborn. This study was done on 120 pregnant women with Bad Obstetric History and 60 pregnant women with normal obstetric history attending Antenatal OP. Each group was screened for Anti TORCH antibodies by Micro ELISA method. The present study has shown IgM antibody seropostivity for Toxoplasma (20%), Rubella (5%), Cytomegalovirus (6.6%) among the BOH group where as in control group seropositivity was 10% for Toxoplasma and were negative for Rubella and CMV. In BOH group IgG antibody seropositivity was Toxoplasma (30%), Rubella (46.6%), CMV (93%) and HSV (6.66%) where as in control group IgG antibody seropositivity for Toxoplasma (16.66%), rubella (40%), CMV (66.66%), HSV-2 (3.33%). Higher rate of seropositivity for IgM and IgG antibodies was seen among pregnant women with BOH compared to those with normal obstetric history suggesting the relationship between TORCH infections and bad obstetric outcome. Thus prenatal screening programmes for TORCH infections over a period of time could be fruitful in decreasing perinatal morbidity and mortality.