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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2015 - IJCMAS--ICV 2015: 85.95 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2017) [Effective from January 1, 2017]For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2015: 85.95
Index Copernicus ICI Journals Master List 2015 - IJCMAS--ICV 2015: 85.95
For more details click here
journals IJCMAS
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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(4): 1736-1743
DOI: https://doi.org/10.20546/ijcmas.2017.604.208


Clinical and Haematobiochemical Alterations Following Administration of Tramadol as Preanaesthetic Analgesic with Xylazine and Propofol Anaesthesia in Canine Ovariohysterectomy
Kumari Chandrakala1, A.K. Sharma1*, Laxmi Kumari2, Raju Prasad3, K.K. Singh4 and Praveen Kumar5
1Department of Surgery and Radiology,
2Touring Veterinary Officer, Animal Husbandry, Jharkhand,
3Department of Veterinary Pharmacology and Toxicology,

4Department of Veterinary Pathology,
 5Department of Veterinary Medicine, Department of Veterinary Surgery and  Radiology, College of Veterinary Science and Animal Husbandry, Birsa Agricultural University, Kanke, Ranchi-834006, Jharkhand, India
*Corresponding author
Abstract:

A total of 5 female dogs of varying age group were admitted at Ranchi Veterinary College in Dept. of Veterinary Surgery and Radiology for elective ovariohysterectomy. All the dogs were premedicated with Atropine sulphate, s/c @ 0.04 mg/kg b.wt. 5 min prior to each treatment. Xylazine @1 mg/kg b.wt –tramadol @ 3 mg/kg b.wt IM thereafter propofol to effect” IV 15 min later and maintained by C.R.I method of propofol @0.3 mg/kg b.wt/min. Rectal temperature and respiration rate exhibited significant alterations whereas heart rate did not show a significant variation. Haemoglobin, packed cell volume, total leucocytic counts and differential leucocytic counts except lymphocytes exhibited non- significant alterations (P>0.05) at different intervals. The values of lymphocytes exhibited a significant fall up to 2 hrs of observation as compared to base line value. A variable and consistent increase (P>0.05) in blood urea nitrogen, creatinine, ALT, total protein could be noticed at different intervals after administration of drugs. However, these changes were non-significant (p>0.05) and within normal physiological limits. Whereas, glucose and AST showed the significant elevation (P<0.05) at different intervals of observation. It is concluded that tramadol as preanaesthetic as analgesia in xylazine and propofol induced and CRI methods for maintenance in canine ovariohysterectomy produced little variation in physiology and haematobiochemical profiles.


Keywords: Bitch, canine, Clinical changes, Haemato biochemical changes, Tramadol, Propofol, ovariohysterectomy
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How to cite this article:

Kumari Chandrakala, A.K. Sharma, Laxmi Kumari, Raju Prasad, K.K. Singh and Praveen Kumar. 2017. Clinical and Haematobiochemical Alterations Following Administration of Tramadol as Preanaethetic Analgesic with Xylazine and Propofol Anaesthesia in Canine Ovariohysterectomy.Int.J.Curr.Microbiol.App.Sci. 6(4): 1736-1743. doi: https://doi.org/10.20546/ijcmas.2017.604.208