Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2015 - IJCMAS--ICV 2015: 85.95 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2017) [Effective from January 1, 2017]For more details click here
Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2015: 85.95
Index Copernicus ICI Journals Master List 2015 - IJCMAS--ICV 2015: 85.95
For more details click here
journals IJCMAS
See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(3): 1612-1620
DOI: https://doi.org/10.20546/ijcmas.2017.603.186


Study of High Level Aminoglycoside Resistance among Enterococci in a Tertiary Care Centre, Navi Mumbai, India
Insha Irfan, S.A. Samant and Rakesh Kumar Mukhia*
Department of Microbiology, MGM Medical College and Hospital, Navi Mumbai, India
*Corresponding author
Abstract:

Enterococci, initially considered as normal commensal of intestinal tract have recently emerged as a medically important pathogen. Incidence of enterococccal infection is significantly high in patients suffering from urinary tract infection, blood stream infection and surgical sites infection. Nosocomial enterococcal infection is also common in organ transplants recipients cancer patients and debilitated patients receiving broad spectrum antibiotics. One of the important causes of development of multi drug resistant Enterococci is antibiotic selective pressure. This organism is considered as second leading cause of hospital acquired infections. The aim of the study was to know the high level aminoglycoside resistance among Enterococci in a tertiary care centre. The study was carried out over a period of 1 year. The isolated Enterococci were identified phenotypically followed by antibiotic susceptibility testing. Out of 2001 specimens showing bacterial growth, 50 strains of Enterococci (2.5%) were isolated. Maximum (3.22%) isolation of Enterococci was from urine samples.  E. faecalis were 47 (94%) and E. faecium were 3 (6%). Out of 50 isolates of enteroccoci, 13 were resistant, 6 were intermediate and 31 were found sensitive. The isolates were found resistant or intermediate using high concentration Gentamicin disc were further tested for MIC level. It was found that 14 total isolates showed MIC ≥ 500mcg. Enterococci show intrinsic low level cross resistance to all aminoglycosides due to decreased update of antibiotics. However recent report shows very high level of acquired resistence to even high level aminoglycoside. Hence all isolates of entrococci need to be tested for high level aminoglycosides.


Keywords: Enterococci, High level aminoglycoside resistance (HLAR).
Download this article as Download

How to cite this article:

Insha Irfan, S.A. Samant and Rakesh Kumar Mukhia. 2017. Study of High Level Aminoglycoside Resistance among Enterococci in a Tertiary Care Centre, Navi MumbaiInt.J.Curr.Microbiol.App.Sci. 6(3): 1612-1620. doi: https://doi.org/10.20546/ijcmas.2017.603.186