|PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
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Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38
Lower respiratory tract infections are among the most common infectious diseases of humans worldwide and continue to be a major cause of morbidity. This study focused on determining the microbial agents of lower respiratory tract infections and the susceptibility profile of bacterial isolates. A total of 585 samples provisionally diagnosed as suffering from lower respiratory tract infections were collected and subjected to microbiological investigations. Out of 585 samples, 345 (58.9%) showed growth of various bacteria. Gram negative bacteria constituted 65.5% of isolates where as gram positive bacteria accounted for 34.5% of the isolates. Klebsiella species was the predominant isolate followed by Staphylococcus aureus and other bacteria. A low level of antibiotic resistance was noted in our study. Of the 191 enterobacterial species, 62 (32.7%) were ESBL producers and 9(3.9%) of gram negative bacteria were MBL producers. Majority of the MBL producers were nonfermenting gram negative bacilli. Among the gram positive bacterial isolates 25 (22.5%) were MRSA strains. Majority of the antibiotic resistant strains were isolated from endotracheal tube secretions. Sensitivity to aminoglycosides and quinolones was good in our study. The present study reveals various pathogens involved in LRTI and their tendency towards antibiotic resistance.