National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
To determine the prevalence of Escherichia coli and the drug susceptibility profile. A twenty –six month retrospective review of culture results of clinical specimens in Ekiti State University Teaching Hospital Medical Microbiology Laboratory from January, 2014 to February, 2016 was done. A total of five hundred and twenty seven (26.4%) Escherichia coli isolates were recovered from 2000 clinical samples for cultures submitted to the laboratory during the 26 months review period. About fifty eight per cent of the isolates were from clinical samples of female patients with 33.6% increased incidence in the age group of 45 years and above. About sixty per cent (n=315/527) of the isolates were from urine samples while 0.4% least isolation rate (n=2/527) was from cerebrospinal fluid samples. The following antibiotics were found to be effective against Escherichia coli isolates; Nitrofurantoin (83.5%)- primarily for urinary tract infection, Ceftriaxone (73.6%), Gentamicin (56.7%) and averagely Ciprofloxacin (49.3%). On the other hand, the following antibiotics showed poor activities; Ampicillin (1.3%), Cefuroxime (20%) and Amoxicillin-clavulanic acid (30.4%). A high rate of multi-drug resistance was noted in this study, especially to commonly used first line antibiotics. Ceftriaxone, Gentamicin and Ciprofloxacin are choices to be considered when treating infections due to E.coli in this geographical location.
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